Articles populaires – Neuroptis Dry Eye Project with ML 7 (Myosin Light Chain Inhibitor)

14 avril 2015

Trial Runners

LINK: http://trialrunners.com Why Trial Runners? Trial Runners unique communication style involves working with clients every step of the way and removing typical communicational hierarchies in order to meet the demands of our clients. We believe that...

Posté par Eric Belot à 20:52 - Commentaires […] - Permalien [#]

Tags: Recruitment, Eye diseases, CRO, Clinica Trias, Runners, Sport

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6 avril 2015

New publications as April 6th, 2015

PUBLICATIONS UP TO APRIL 6TH 2015 1. Acta Ophthalmol. 2015 Apr 2. doi: 10.1111/aos.12710. [Epub ahead of print] Autologous serum and plasma rich in growth factors in ophthalmology: preclinical and clinical studies. Anitua E 1, Muruzabal F, Tayebba A,...

Posté par Eric Belot à 18:12 - Commentaires […] - Permalien [#]

Tags: publications, Dry eye, treatment, DED, 2015, Statistics

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1 avril 2015

The TearScience solution for Meibomian Gland Dysfunction

LINK: http://tearscience.com/en/ Give MGD a Second Glance Meibomian Gland Dysfunction is treatable. The TearScience® Solution for MGD allows eye care professionals to safely and effectively identify, diagnose, and treat MGD in four easy steps. With 86%...

Posté par Eric Belot à 14:37 - Commentaires […] - Permalien [#]

Tags: Meibomian, Medical Device, Tearscience website, Tarsal glands Meibomius glands dysfunction, treatment, Tearfilm quality

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10 mars 2015

DRY EYE PUBLICATION MARCH 10th 2015

1. Invest Ophthalmol Vis Sci. 2015 Mar 5. pii: IOVS-14-15890. doi: 10.1167/iovs.14-15890. [Epub ahead of print] Corneoscleral limbus in glaucoma patients: in vivo confocal microscopy and immunocytological study. Mastropasqua R 1, Agnifili L 2, Fasanella...

Posté par Eric Belot à 12:37 - Commentaires […] - Permalien [#]

Tags: Tarsal glands Meibomius glands protection, Meibomian, Tarsal glands Meibomius glands dysfunction, Dry eye, treatment, Tearfilm quality

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12 juin 2016

Nonmuscle myosin light chain kinase activity modulates radiation-induced lung injury.

Pulm Circ. 2016 Jun;6(2):234-9. doi: 10.1086/686491. Nonmuscle myosin light chain kinase activity modulates radiation-induced lung injury. Wang T1, Mathew B2, Wu X3, Shimizu Y3, Rizzo AN4, Dudek SM4, Weichselbaum RR5, Jacobson JR4, Hecker L6, Garcia JG3....

Posté par Eric Belot à 17:14 - Commentaires […] - Permalien [#]

Tags: ML7, MLCK inhibitor, 2016, bronchoalveolar lavage

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5 février 2015

6-MONTH STABILITY REPORT

LIEN: OCTALIA_STABILITE_2013_115 0.05%ML7 AND PLACEBO EYE-DROPS CONTAINING 0.3%HPMC (BATCHES E728-1’ AND E728-2’) OR 0.1%HEC (BATCHES E728-3 AND E728-4) 6-MONTH STABILITY REPORT NEUROPTIS Issued date: February 07th, 2014 TABLE OF CONTENTS 1. Introduction...

Posté par Eric Belot à 13:55 - Commentaires […] - Permalien [#]

Tags: Stability Formulated ML7 eye drop, ML7, Dry eye, DED, Preservative-free, Stability study

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5 août 2015

SHIRE ACQUIRES FORESIGHT BIOTHERAPEUTICS FOR $300MN

SHIRE ACQUIRES FORESIGHT BIOTHERAPEUTICS FOR $300MN Shire to Buy Foresight Biotherapeutics for $300 Million Shire PLC has agreed to buy a privately held eye-drug company for $300 million in a deal that would add another promising ophthalmology treatment...

Posté par Eric Belot à 19:04 - Commentaires […] - Permalien [#]

Tags: 2015, Shire, Acquisition, Biotherapeutics, Viral conjunctivis

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7 septembre 2015

Melatonin inhibits the Migration of Colon Cancer RKO cells by Down-regulating MLCK Expression through Cross-talk with p38 MAPK

Asian Pac J Cancer Prev. 2015;16(14):5835-42. Melatonin inhibits the Migration of Colon Cancer RKO cells by Down-regulating Myosin Light Chain Kinase Expression through Cross-talk with p38 MAPK. Papers in the journal Asian Pacific Journal of Cancer Prevention:...

Posté par Eric Belot à 21:55 - Commentaires […] - Permalien [#]

Tags: ML7, MLCK inhibitor, Colon Cancer, Melatonin, Migration of cells

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29 juin 2015

MLCK inhibitor ML7 improves vascular endothelial dysfunction via tight junction regulation in a rabbit model of atherosclerosis

Myosin light chain kinase inhibitor ML7 improves vascular endothelial dysfunction via tight junction regulation in a rabbit model of atherosclerosis Vascular endothelial dysfunction (VED) is an important factor in the initiation and development of atherosclerosis...

Posté par Eric Belot à 22:06 - Commentaires […] - Permalien [#]

Tags: ML7, MLCK inhibitor, Atherosclerosis, vascular endothelial dysfunction

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29 août 2015

NEW PUBLICATION UPTO AUG 21TH 2015

NEW PUBLICATION UPTO AUG 21TH 2015 Search - American Academy of Ophthalmology http://www.aao.org J Ocul Pharmacol Ther. 2015 Aug 21. [Epub ahead of print] Semifluorinated Alkane Eye Drops for Treatment of Dry Eye Disease-A Prospective, Multicenter Noninterventional...

Posté par Eric Belot à 18:14 - Commentaires […] - Permalien [#]

Tags: publications, Dry eye, DED, 2015, News

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15 août 2015

The Rho-GTPase effector ROCK regulates meiotic maturation of the bovine oocyte via MLC phosphorylation

The Rho-GTPase effector ROCK regulates meiotic maturation of the bovine oocyte via myosin light chain phosphorylation and cofilin phosphorylation. Gene Information - OKdb General Comment upstream of Hippo signaling NCBI Summary: This gene encodes a protein...

Posté par Eric Belot à 13:59 - Commentaires […] - Permalien [#]

Tags: ML7, Research, MLCK inhibitor, Bovine oocyte, Rocck

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4 juin 2015

More patients experience phantom eye symptoms every day, say University of Liverpool researchers

More patients experience phantom eye symptoms every day, say University of Liverpool researchers More patients experience phantom eye symptoms every day, say University of Liverpool researchers Researchers from the University of Liverpool have found that...

Posté par Eric Belot à 21:12 - Commentaires […] - Permalien [#]

Tags: 2015, Melanoma, Phantom eye, cancer, metastasis

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26 juin 2015

Innovative formula prevents risks, painful treatments in people with secondary blindness

Innovative formula prevents risks, painful treatments in people with secondary blindness Innovative formula prevents risks, painful treatments in people with secondary blindness The Mexican company "Medical and Surgical Center for Retina" created a way...

Posté par Eric Belot à 19:47 - Commentaires […] - Permalien [#]

Tags: formulation, 2015, Nanoparticules, Nanotechnologies, Blindness

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10 mai 2015

Dry eye strikes most often in spring

Dry eye strikes most often in spring Health News and Information - News Medical from News-Medical.Net - Latest Medical News and Research from Around the World http://www.news-medical.net New ophthalmology research from the University of Miami shows that...

Posté par Eric Belot à 11:26 - Commentaires […] - Permalien [#]

Tags: publications, Dry eye, DED, 2015, Allergy

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10 mai 2015

Dry eye symptoms correlated with non-ocular conditions

Dry eye symptoms correlated with non-ocular conditions Strategies for Managing Dry Eye Richard L. Lindstrom, MD: Dry eye syndrome affects approximately 15% of the U.S. population, and the prevalence in Asia may be as high as 20% to 30%.1 Numerous underlying...

Posté par Eric Belot à 15:24 - Commentaires […] - Permalien [#]

Tags: publications, Dry eye, DED, 2015, NON OCULAR CONDITIONS

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24 avril 2015

BIOTECHFINANCES n°679 lundi 27 avril 2015

Biotech finances : Actualités Biotechs, Medtechs, Cap Risque : Biotech Finances BIOTECH FINANCES Editions Européennes de l'Innovation est un éditeur Européen qui diffuse une lettre d'information hebdomadaire des magazines et des produits spécialisés (cartographie)...

Posté par Eric Belot à 20:29 - Commentaires […] - Permalien [#]

Tags: Biotech Finances, Financing, Biomap, Biotechnology, Biovision

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20 avril 2015

PUBLICATIONS UP TO APRIL 20th 2015

UPCOMING NEWS 1. Ocul Surf. 2015 Apr;13(2):118-132. doi: 10.1016/j.jtos.2014.12.001. Epub 2015 Jan 15. Clinical Guidelines for Management of Dry Eye Associated with Sjögren Disease. Foulks GN 1, Forstot SL 2, Donshik PC 3, Forstot JZ 4, Goldstein MH 5,...

Posté par Eric Belot à 17:32 - Commentaires […] - Permalien [#]

Tags: publications, Dry eye, 2015, ophthalmic news, update

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11 avril 2015

Ocular Therapeutix

Link: http://www.ocutx.com OCULAR THERAPEUTIX EYE DRUG FAILS SECOND STUDY 7 Apr 2015 | PharmaBusiness Daily Ocular Therapeutix says its lead eye drug failed to meet one of the main goals in a second late-stage study, Reuters reports. The drug, OTX-DP,...

Posté par Eric Belot à 19:49 - Commentaires […] - Permalien [#]

Tags: treatment, Case Control study, New Therapies, Ocular Therapeutics, Plug

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25 février 2015

LIGHT DEGRADATION OF ML7 FORMULATIONS BY OCTALIA TECHNOLOGIES CRO: CONCLUSION

Octalia Technologies - Vallauris, Alpes Maritimes, Côte d'azur, 06 Octalia Technologies is a fully independent drug delivery company specialized in the field of ophthalmology. Formulation, pharmaceutical drug development and applied research that integrate...

Posté par Eric Belot à 15:48 - Commentaires […] - Permalien [#]

Tags: ML7, formulation, CRO, Light Degradation, Octalia

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23 mars 2015

Influence of Lachrymal Substitutes on Tear Film Thickness in Patients With Moderate Dry Eye Syndrome

Influence of Lachrymal Substitutes on Tear Film Thickness in Patients With Moderate Dry Eye Syndrome This study has been completed. Sponsor: Medical University of Vienna Information provided by (Responsible Party): Gerhard Garhofer, Medical University...

Posté par Eric Belot à 17:47 - Commentaires […] - Permalien [#]

Tags: treatment, Tearfilm quality, Case Control study, DED, 2013

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30 janvier 2015

Publication on ML7 in IOVS 2013

Article complet: iovs Ocular Inflammation and Corneal Permeability Alteration by Benzalkonium Chloride in Rats: A Protective Effect of a Myosin light chain kinase Inhibitor. Marie Thérèse DROY-LEFAIX, PhD, 1 Lionel BUENO, PhD, 1 Philippe CARON, MD, 1...

Posté par Eric Belot à 20:08 - Commentaires […] - Permalien [#]

Tags: ML7, Animals Efficacy, IOVS, Initial Study

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9 avril 2015

U.S. FDA Grants Priority Review to Lifitegrast NDA for the Treatment of Dry Eye Disease in Adults

Shire has added a new press release to the Company's web site. To view the release, please click on the link below: http://www.shire.com/shireplc/en/investors/investorsnews/irshirenews?id=1089 See full text copy below: U.S. FDA Grants Priority Review...

Posté par Eric Belot à 21:41 - Commentaires […] - Permalien [#]

Tags: 2015, Shire, Lifitegrast, NDA

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10 juin 2015

Optometrist seeing more patients with dry eyes

Optometrist seeing more patients with dry eyes Optometrist seeing more patients with dry eyes SOMERSWORTH - Dr. Susan Haskell, a doctor of optometry at Eyesight Ophthalmic Services, is seeing an increasing number of patients with dry eye syndrome."I see...

Posté par Eric Belot à 12:29 - Commentaires […] - Permalien [#]

Tags: Dry eye, DED, Optometrist, Patient.

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16 mars 2015

New articles on Dry Eye Syndrome. Week ending March 13th, 2015

1. Cont Lens Anterior Eye. 2015 Mar 10. pii: S1367-0484(15)00021-1. doi: 10.1016/j.clae.2015.02.002. [Epub ahead of print] Ocular surface involvements in ectrodactyly-ectodermal dysplasia-cleft syndrome. Kennedy DP 1, Chandler JW 1, McCulley JP 2. Author...

Posté par Eric Belot à 12:10 - Commentaires […] - Permalien [#]

Tags: publications, Dry eye, Epidemiology, Risk Factor

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23 mars 2015

Intraductal Meibomian Gland Probing Trial (MGP)

Intraductal Meibomian Gland Probing Trial (MGP) This study is currently recruiting participants. (see Contacts and Locations ) Verified October 2014 by Massachusetts Eye and Ear Infirmary Sponsor: Pedram Hamrah, MD Information provided by (Responsible...

Posté par Eric Belot à 22:15 - Commentaires […] - Permalien [#]

Tags: Tarsal glands Meibomius glands protection, Meibomian, Tarsal glands Meibomius glands dysfunction, Case Control study

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