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Neuroptis Dry Eye Project with ML 7 (Myosin Light Chain Inhibitor)
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15 mai 2015

Eleven Biotherapeutics Presents Clinical Data on EBI-005 for the Treatment of Dry Eye Disease and Allergic Conjunctivitis

Eleven Biotherapeutics Presents Clinical Data on EBI-005 for the Treatment of Dry Eye Disease and Allergic Conjunctivitis
Eleven Biotherapeutics Presents Clinical Data on EBI-005 for the Treatment of Dry Eye Disease and Allergic Conjunctivitis at ARVO 2015 Annual Meeting NASDAQ:EBIO - Finances Eleven Biotherapeutics, Inc. http://www.finances.com Eleven Biotherapeutics, Inc....
Posté par Eric Belot à 17:12 - Commentaires […] - Permalien [#]
Tags: Dry eye,  treatment,  DED,  2015,  Efficacy,  Eye Drop,  Clinica Trias,  ARVO,  Inflammation,  Allergy,  Conjunctivitis,  EBI-005,  Eleven Biotherapeutics

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25 avril 2015

EVALUATION OF TOPICAL ADMINISTRATIONS OF ML7 IN A RAT MODEL OF SCOPOLAMINE-INDUCED DRY EYE. SIGNED REPORT.

EVALUATION OF TOPICAL ADMINISTRATIONS OF ML7 IN A RAT MODEL OF SCOPOLAMINE-INDUCED DRY EYE. SIGNED REPORT.
Contract Research Organization: Ophthalmology Research - Iris Pharma Iris Pharma, a Contract Research Organization, provides preclinical and clinical research in ophthalmology: ocular safety, efficacy, ocular pharmacokinetics, clinical trials, bioanalytical...
Posté par Eric Belot à 13:33 - Commentaires […] - Permalien [#]
Tags: ML7,  Dry eye,  DED,  2014,  Animals Efficacy,  IRIS Pharma,  Preservative-free,  Statistics,  Neuroptis Biotech,  Precinical,  Signed Study,  Rats,  Scopolamine

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2 novembre 2015

NEW PUBLICATIONS UPTO OCT. 31ST 2015

NEW PUBLICATIONS UPTO OCT. 31ST 2015
NEW PUBLICATIONS UPTO OCT. 31ST 2015 1. Cornea. 2015 Oct 27. [Epub ahead of print] Efficacy and Safety of Carbomer-Based Lipid-Containing Artificial Tear Formulations in Patients With Dry Eye Syndrome. Chung SH 1, Lim SA , Tchach H . Author information:...
Posté par Eric Belot à 20:53 - Commentaires […] - Permalien [#]
Tags: publications,  Tarsal glands Meibomius glands protection,  ML7,  Tarsal glands Meibomius glands dysfunction,  Dry eye,  diagnosis,  DED,  New Therapies,  MLCK inhibitor,  News

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18 septembre 2015

NEW PUBLICATIONS UPTO SEPTEMBER 13TH 2015

NEW PUBLICATIONS UPTO SEPTEMBER 13TH 2015
NEW PUBLICATIONS UPTO SEPTEMBER 13TH 2015 Put the Squeeze on Meibomian Gland Disease Meibomian gland dysfunction (MGD) can lead to inflammation of the meibomian glands (meibomianitis) and excess oil in the tear film. Bacteria and other substances often...
Posté par Eric Belot à 19:51 - Commentaires […] - Permalien [#]
Tags: publications,  Meibomian,  glands,  Tarsal glands Meibomius glands dysfunction,  Dry eye,  treatment,  DED,  2015,  Optometrist,  News,  Sjögren's syndrome,  doxycycline

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22 juin 2015

NEWS: NEW PUBLICATIONS UPTO JUNE 21ST 2015

NEWS: NEW PUBLICATIONS UPTO JUNE 21ST 2015
Eye - Figure 3 for article: In vivo detection of clinically non-apparent ocular surface inflammation in patients with meibomian gland dysfunction-associated refractory dry eye symptoms: a pilot study Eye is the official journal of the Royal College of...
Posté par Eric Belot à 14:53 - Commentaires […] - Permalien [#]
Tags: publications,  Tarsal glands Meibomius glands protection,  Meibomian,  ocular surface,  Dry eye,  diagnosis,  treatment,  DED,  2015,  Inflammation,  News,  refractory

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30 juin 2015

NEWS/PUBLICATIONS UPTO JUNE 29TH 2015

NEWS/PUBLICATIONS UPTO JUNE 29TH 2015
Efficiency and safety of subconjunctival injection of anti-VEGF agent | DDDT Efficiency and safety of subconjunctival injection of anti-VEGF agent - bevacizumab - in treating dry eye Xiaodan Jiang,* Huibin Lv,* Weiqiang Qiu, Ziyuan Liu, Xuemin Li, Wei...
Posté par Eric Belot à 12:40 - Commentaires […] - Permalien [#]
Tags: publications,  Tarsal glands Meibomius glands protection,  Meibomian,  ocular surface,  Dry eye,  diagnosis,  treatment,  DED,  2015,  Inflammation,  News,  refractory

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26 octobre 2015

NEW PUBLICATIONS UPTO OCT. 24TH 2015

NEW PUBLICATIONS UPTO OCT. 24TH 2015
NEW PUBLICATIONS UPTO OCT. 24TH 2015 Ocular Manifestations of Autoimmune Disease Rheumatoid arthritis, juvenile rheumatoid arthritis, Sjögren's syndrome, the seronegative spondyloarthropathies, systemic lupus erythematosus, multiple sclerosis, giant...
Posté par Eric Belot à 13:55 - Commentaires […] - Permalien [#]
Tags: publications,  Tarsal glands Meibomius glands protection,  Tarsal glands Meibomius glands dysfunction,  Dry eye,  diagnosis,  treatment,  DED,  2015,  News

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31 janvier 2015

Note de synthèse sur les études réalisées par Iris Pharma

Note de synthèse sur les études réalisées par Iris Pharma
Lien: Note_de_synth_se_sur_les__tudes_r_alis_es_par_IrisPharma Note de synthèse sur les études réalisées par Iris Pharma Etude n°1 : Test de tolérance locale 1/ But de l’étude Evaluation de l’effet de 3 concentrations de ML7 (0,1%, 0,03% et 0,01%) chez...
Posté par Eric Belot à 18:48 - Commentaires […] - Permalien [#]
Tags: patents,  ML7,  formulation,  pharmacology,  toxicity,  2014,  Animals Efficacy,  IRIS Pharma,  Preservative-free,  Systemic penetration

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30 novembre 2015

Role of myosin light chain and myosin light chain kinase in advanced glycation end product-induced endothelial hyperpermeability

Role of myosin light chain and myosin light chain kinase in advanced glycation end product-induced endothelial hyperpermeability
Diab Vasc Dis Res. 2015 Nov 24. pii: 1479164115610469. [Epub ahead of print] Role of myosin light chain and myosin light chain kinase in advanced glycation end product-induced endothelial hyperpermeability in vitro and in vivo. Wu F 1, Guo X 2, Xu J 2,...
Posté par Eric Belot à 21:12 - Commentaires […] - Permalien [#]
Tags: publications,  ML7,  2015,  MLCK,  MLCK inhibitor,  Glycation,  endothelial,  hyperpermeability

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8 janvier 2015

Study IRIS Pharma: evaluation of effectiveness of eye drop ML7 formulation in a rat modele of scopolamine-induced dry eye

Study IRIS Pharma: evaluation of effectiveness of eye drop ML7 formulation in a rat modele of scopolamine-induced dry eye
COMPTE RENDU DE L'ÉTUDE D'EFFICACITÉ 1. Summary Purpose: The aim of the study was to evaluate the therapeutic potential of topical applied ML7 formulation in a rat model of scopolamine-induced dry eye. Method: Dry eye symptoms were induced in albino Lewis...
Posté par Eric Belot à 18:56 - Commentaires […] - Permalien [#]
Tags: ML7,  formulation,  Case Control study,  2014,  Animals Efficacy,  Eye Drop,  IRIS Pharma,  Preservative-free,  Statistics

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17 octobre 2015

NEW PUBLICATIONS UPTO OCT. 10TH 2015

NEW PUBLICATIONS UPTO OCT. 10TH 2015
NEW PUBLICATIONS UPTO OCT. 10TH 2015 Eyelid Ptosis Surgery For more than 20 years, Cosmetic Oculofacial Plastic Surgeon Dr Amiya Prasad has helped patients from around the world affected by ptosis, commonly referred to as "droopy eyelid" see and look...
Posté par Eric Belot à 17:08 - Commentaires […] - Permalien [#]
Tags: publications,  Dry eye,  treatment,  DED,  2015,  News

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22 décembre 2015

NEW PUBLICATIONS UPTO DECEMBER 18TH 2015

NEW PUBLICATIONS UPTO DECEMBER 18TH 2015
NEW PUBLICATIONS UPTO DECEMBER 18TH 2015 Continuing Education > Recalibrate Dry Eye Management - By Mile Brujic The tear film is in a state of delicate balance. Likewise, we must carefully balance a dry eye patient's risk factors, symptoms and clinical...
Posté par Eric Belot à 17:10 - Commentaires […] - Permalien [#]
Tags: publications,  Tarsal glands Meibomius glands protection,  Dry eye,  DED,  2015,  News,  Sjögren's syndrome

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1 décembre 2015

NEW PUBLICATIONS UPTO NOV. 27TH 2015

NEW PUBLICATIONS UPTO NOV. 27TH 2015
NEW PUBLICATIONS UPTO NOV. 27TH 2015 IOVS | Design of a subtarsal ultrasonic transducer for mild hyperthermia of meibomian glands treating Dry Eye Disease http://iovs.arvojournals.org 1. Curr Med Res Opin. 2015 Nov 27:1-26. [Epub ahead of print] Sodium...
Posté par Eric Belot à 13:25 - Commentaires […] - Permalien [#]
Tags: publications,  Tarsal glands Meibomius glands protection,  Tarsal glands Meibomius glands dysfunction,  Dry eye,  DED,  Hyalunoric Acid,  News

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30 avril 2015

Clinical Research Study Demonstrates EyePromise® EZ Tears Relieves Dry Eye Symptoms and Discomfort Fast

Clinical Research Study Demonstrates EyePromise® EZ Tears Relieves Dry Eye Symptoms and Discomfort Fast
Clinical Research Study Demonstrates EyePromise® EZ Tears Relieves Dry Eye Symptoms and Discomfort Fast Publication: Nutritiontearfilm Apr 13, 2015, 08:30 ET from ZeaVision ST. LOUIS, April 13, 2015 /PRNewswire/ -- People suffering with burning, red,...
Posté par Eric Belot à 18:40 - Commentaires […] - Permalien [#]
Tags: publications,  Dry eye,  Tearfilm quality,  DED,  2015,  Clinical Trial,  EyePromise,  Nutrition,  ZeaVision

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31 août 2015

NEW PUBLICATIONS UPTO AUG. 31ST 2015 ON DRY EYE DIAGNOSIS AND THERAPEUTICS

NEW PUBLICATIONS UPTO AUG. 31ST 2015 ON DRY EYE DIAGNOSIS AND THERAPEUTICS
NEW PUBLICATIONS UPTO AUG. 31ST 2015 ON DRY EYE DIAGNOSIS AND THERAPEUTICS Glaucoma and Dry Eye: A Tough Combo How chronic glaucoma treatment can give rise to ocular surface disease, and how you can treat them both. Mark B. Abelson, MD, CM, FRCSC, FARVO,...
Posté par Eric Belot à 20:24 - Commentaires […] - Permalien [#]
Tags: publications,  Dry eye,  diagnosis,  treatment,  DED,  2015,  Glaucoma,  News,  Diquafosol

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5 août 2015

NEW PUBLICATIONS UPTO AUG 1ST 2015

NEW PUBLICATIONS UPTO AUG 1ST 2015
NEW PUBLICATIONS UPTO AUG 1ST 2015 Long-Term (3 Year) Effects of a Single Thermal Pulsation System Treatment on Meibomian Gland Function and Dry Eye Symptoms : 455117X_21184_0187 1. Cornea. 2015 Jul 29. [Epub ahead of print] Effectiveness of Autologous...
Posté par Eric Belot à 01:00 - Commentaires […] - Permalien [#]
Tags: publications,  Meibomian,  Dry eye,  DED,  2015,  New Therapies,  Sjögren's syndrome,  Autologous Serum

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1 octobre 2015

NEW PUBLICATIONS ONTO SEPT. 25TH 2015

NEW PUBLICATIONS ONTO SEPT. 25TH 2015
NEW PUBLICATIONS ONTO SEPT. 25TH 2015 An Overview on Dry Eye Treatment: Approaches for Cyclosporin A Delivery The Scientific World Journal is a peer-reviewed, open access journal covering a wide range of subjects in science, technology, and medicine....
Posté par Eric Belot à 21:22 - Commentaires […] - Permalien [#]
Tags: publications,  Tarsal glands Meibomius glands dysfunction,  Dry eye,  diagnosis,  treatment,  DED,  2015,  News,  Sjögren's syndrome

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9 septembre 2015

Strong efficacy of LipiFlow demonstrated across 31 peer-reviewed reports

Strong efficacy of LipiFlow demonstrated across 31 peer-reviewed reports
Strong efficacy of LipiFlow demonstrated across 31 peer-reviewed reports Long-term efficacy of a single LipiFlow procedure evaluated and reported in both sponsored and independent studies MORRISVILLE, N.C. ─ September 8, 2015 ─ TearScience , a privately...
Posté par Eric Belot à 15:32 - Commentaires […] - Permalien [#]
Tags: publications,  Meibomian,  Lipidflow,  Tearscience website,  Dry eye,  DED,  2015

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2 mai 2015

Functional Impairment of Reading Ability in Dry Eye Patients and Effects of Sustained Reading on the Ocular Surface

Functional Impairment of Reading Ability in Dry Eye Patients and Effects of Sustained Reading on the Ocular Surface
Functional Impairment of Reading Ability in Dry Eye Patients and Effects of Sustained Reading on the Ocular Surface - Tabular View - ClinicalTrials.gov Patients with known dry eye as well as normal healthy control subjects with no ocular surface diseases...
Posté par Eric Belot à 19:23 - Commentaires […] - Permalien [#]
Tags: ocular surface,  Dry eye,  DED,  2015,  Recruiting,  Allergan,  Clinical Trial,  Functional Impairment,  Reading ability

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15 juillet 2015

UNEXPECTED PROTECTIVE EFFECT OF ML7 -MLCK INHIBITOR- ON TARSAL GLANDS

UNEXPECTED PROTECTIVE EFFECT OF ML7 -MLCK INHIBITOR- ON TARSAL GLANDS
Ocular inflammation and corneal alteration by benzalkonium chlorids in rabbits: an unexpected protective effect of ML7 - a myosin light chain kinase inhibitor - on tarsal glands LIEN: Ocular_inflammation_and_corneal_alteration_by_benzalkonium_chlorids_in_rabbits_STUDY_BOSTON_MONTREAL_...
Posté par Eric Belot à 17:59 - Commentaires […] - Permalien [#]
Tags: Tarsal glands Meibomius glands protection,  ML7,  Tarsal glands Meibomius glands dysfunction,  Trial Meibomian gland Tarsal gland,  treatment,  Precinical,  MLCK inhibitor,  Rabbits

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2 juillet 2015

Meibography is the first and only definitive test for any form of dry eye.

Meibography is the first and only definitive test for any form of dry eye.
Meibomian Gland Dysfunction | Treatment | TearScience TearScience® is the only company dedicated to identifying, diagnosing, and treating MGD, the leading cause of dry eye, with an FDA-cleared solution that restores gland function. http://tearscience.com...
Posté par Eric Belot à 19:22 - Commentaires […] - Permalien [#]
Tags: Tearscience website,  Tarsal glands Meibomius glands dysfunction,  Dry eye,  diagnosis,  DED,  2015,  Devices,  LipiFlow

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7 avril 2015

Herantis Pharma’s Phase 2 Dry Eye study recruitment completed ahead of schedule

Herantis Pharma’s Phase 2 Dry Eye study recruitment completed ahead of schedule
Herantis Pharma’s Phase 2 Dry Eye study recruitment completed ahead of schedule Herantis Pharma’s Phase 2 Dry Eye study recruitment completed ahead of schedule Herantis Pharma Plc Company release 11 March 2015 at 10:00 am Dry Eye Herantis Pharma Plc has...
Posté par Eric Belot à 18:11 - Commentaires […] - Permalien [#]
Tags: Dry eye,  treatment,  Case Control study,  DED,  2015,  Phase 23,  Herantis Pharma,  Recruitment,  cis-UCA

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5 février 2015

ML7 FORMULATION FOR DRY EYE THERAPY

ML7 FORMULATION FOR DRY EYE THERAPY
LINK: OCTALIA_STABILITE_2013_115 ML7 FORMULATION FOR DRY EYE THERAPY STEP B – FORMULATION INVESTIGATIONS NEUROPTIS Issued date: February 07th, 2014 TABLE OF CONTENTS 1. Introduction ...........................................................................................................................
Posté par Eric Belot à 19:47 - Commentaires […] - Permalien [#]
Tags: Stability Formulated ML7 eye drop,  HPMC viscosing agent,  ML7,  cyclodextrin,  dosage,  formulation,  toxicity,  2013

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27 mars 2015

Clinical Trials in 2014

Clinical Trials in 2014
Phase 2/3 Dose-Ranging Study of the Safety and Efficacy of OTX-101 in the Treatment of Keratoconjunctivitis Sicca This study is currently recruiting participants. (see Contacts and Locations ) Verified October 2014 by Ocular Technologies SARL Sponsor:...
Posté par Eric Belot à 17:08 - Commentaires […] - Permalien [#]
Tags: treatment,  DED,  2014,  Efficacy,  Keratoconjunctivitis Sicca,  OTX-101,  Ocular Technologies,  Phase 23,  Safety

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11 août 2015

Biphasic force response to iso-velocity stretch in airway smooth muscle.

Biphasic force response to iso-velocity stretch in airway smooth muscle.
Biphasic force response to iso-velocity stretch in airway smooth muscle. Biphasic force response to iso-velocity stretch in airway smooth muscle Airway smooth muscle (ASM) in vivo is constantly subjected to oscillatory strain due to tidal breathing and...
Posté par Eric Belot à 04:02 - Commentaires […] - Permalien [#]
Tags: ML7,  2015,  MLCK inhibitor,  Science,  Biphasic Force,  Smooth Muscle,  iso-velocity

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