Articles populaires – Neuroptis Dry Eye Project with ML 7 (Myosin Light Chain Inhibitor)

27 juillet 2015

Interaction in endothelium of nmMLCK and the NF-κB pathway is critical to lipopolysaccharide-induced vascular hyporeactivity.

Interaction in endothelium of non-muscular myosin light-chain kinase and the NF-κB pathway is critical to lipopolysaccharide-induced vascular hyporeactivity. 0319 : Non muscular myosin light chain kinase (nmMLCK) and NF-κB pathway interaction in endothelium...

Posté par Eric Belot à 13:44 - Commentaires […] - Permalien [#]

Tags: ML7, 2015, Inflammation, MLCK, MLCK inhibitor, Fundamental Study, Science

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9 décembre 2015

NEW PUBLICATIONS ABOUT DRY EYE SYNDROM UPTO DEC. 4TH 2015

NEW PUBLICATIONS ABOUT DRY EYE SYNDROM UPTO DEC. 4TH 2015 SciStream This free news service SciBite.com, we hope you find it useful. SciBITES scans 100s of biomedically relevant websites every second of every day, hunting for the targets, indications,...

Posté par Eric Belot à 15:32 - Commentaires […] - Permalien [#]

Tags: publications, Dry eye, DED, 2015, Drug development, News

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13 avril 2015

Publications up to April 13 th 2015

PubMed Results Items 1 - 13 of 13 1. Cutan Ocul Toxicol. 2015 Apr 8:1-5. [Epub ahead of print] The ocular surface side effects of an anti-psychotic drug, clozapine. Ceylan E 1, Ozer MD, Yilmaz YC, Kartal B, Yildiz Ekinci D, Çinici E, Aksu Ceylan N. Author...

Posté par Eric Belot à 21:32 - Commentaires […] - Permalien [#]

Tags: publications, pictures, glands, Dry eye, diagnosis, DED, 2015, Scintigraphy

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17 avril 2015

Amakem Therapeutics

AMAKEM THERAPEUTICS Amakem is a clinical stage ophthalmology company developing innovative new treatments for serious eye conditions. The Company’s lead program is based on AMA0076, a novel, locally-acting Rho kinase (ROCK) inhibitor, in clinical development...

Posté par Eric Belot à 20:24 - Commentaires […] - Permalien [#]

Tags: Biotech Finances, Dry eye, Rho Kinase Inhibitor, DED, Glaucoma, Amakem Therapeutics, Belgium, Venture

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24 mars 2015

Hyaluronic Acid Gels for Upper Lid Retraction in Active Stage Thyroid Eye Disease (HALR)

Hyaluronic Acid Gels for Upper Lid Retraction in Active Stage Thyroid Eye Disease (HALR) This study is currently recruiting participants. (see Contacts and Locations ) Verified December 2014 by University of California, Los Angeles Sponsor: University...

Posté par Eric Belot à 16:48 - Commentaires […] - Permalien [#]

Tags: Dry eye, Case Control study, 2014, Cosmetic, Hyalunoric Acid, Lid retraction, Recruiting, Thyroid Eye Disease

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3 mai 2015

CEREP STUDY ON ML7 WITH BIOPRINT

CEREP Cerep provides all services to support drug discovery and hit-to-lead development, from combinatorial chemistry, high throughput screening (HTS) and profiling (HTP), medicinal and computational chemistry, molecular, cellular and animal pharmacology,...

Posté par Eric Belot à 16:19 - Commentaires […] - Permalien [#]

Tags: ML7, pharmacology, Safety, Bioprint, Cerep, Profile, Study

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4 mai 2015

Inhibition of myosin light chain kinase reduces NADPH oxidase-mediated oxidative injury in rat brain following cerebral ischemia

Inhibition of myosin light chain kinase reduces NADPH oxidase-mediated oxidative injury in rat brain following cerebral ischemia/reperfusion. Inhibition of myosin light chain kinase reduces NADPH oxidase-mediated oxidative injury in rat brain following...

Posté par Eric Belot à 18:57 - Commentaires […] - Permalien [#]

Tags: ML7, 2015, MLCK, Links, Lung, Neurology, Reperfusion, ischemia

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13 juillet 2015

NEW PUBLICATIONS UPTO JULY THE 11TH, 2015 ON DED

NEW PUBLICATIONS UPTO JULY THE 11TH, 2015 ON DED Ocular Adverse Effects of Systemic Treatment With Isotretinoin Objective To examine whether isotretinoin therapy could result in deleterious ocular effects, as previously described in case report studies....

Posté par Eric Belot à 21:41 - Commentaires […] - Permalien [#]

Tags: publications, Dry eye, diagnosis, treatment, DED, 2015, Sjögren's syndrome, Steroids

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20 juillet 2015

NEW PUBLICATIONS UPTO JULY 18TH 2015

NEW PUBLICATIONS UPTO JULY 18TH 2015 A Pragmatic Approach to the Management of Dry Eye Disease:... : Optometry & Vision Science Dry eye disease (DED) is a highly prevalent chronic ocular disorder that can lead to significant discomfort and visual disturbance....

Posté par Eric Belot à 14:24 - Commentaires […] - Permalien [#]

Tags: publications, Meibomian, Tarsal glands Meibomius glands dysfunction, Dry eye, diagnosis, DED, 2015, New Therapies

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26 mai 2015

News through publications up to May 25th 2015

JBP485 promotes tear and mucin secretion in ocular surface epithelia Journal name: Scientific Reports Volume: 5, Article number: 10248 DOI: doi:10.1038/srep10248 Dry eye syndrome (DES) is one of the most frequently encountered ocular diseases. Epidemiological...

Posté par Eric Belot à 20:31 - Commentaires […] - Permalien [#]

Tags: publications, Dry eye, Tearfilm quality, DED, 2015, New Therapies, Mucin

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11 août 2015

NEW PUBLICATIONS UPTO AUG. 8TH 2015

NEW PUBLICATIONS UPTO AUG. 8TH 2015 Brief Report: Ultrasonographic Assessment of Salivary Gland Response to Rituximab in Primary Sjögren's Syndrome Jousse-Joulin, S., Devauchelle-Pensec, V., Cornec, D., Marhadour, T., Bressollette, L., Gestin, S., Pers,...

Posté par Eric Belot à 20:33 - Commentaires […] - Permalien [#]

Tags: publications, 2015, News, Sjögren's syndrome, AIDS, Gougerot Sjögren's Syndrom, Thymosin, Salivary Gland

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8 juin 2015

Rho kinase-dependent actin turnover and actomyosin disassembly are necessary for mouse spinal neural tube closure.

Rho kinase-dependent actin turnover and actomyosin disassembly are necessary for mouse spinal neural tube closure. Escuin S 1, Vernay B 1, Savery D 1, Gurniak CB 2, Witke W 2, Greene ND 1, Copp AJ 3. Author information Abstract The cytoskeleton is widely...

Posté par Eric Belot à 18:22 - Commentaires […] - Permalien [#]

Tags: ML7, Rho Kinase Inhibitor, 2015, MLCK, MLCK inhibitor, Mouse, Neurulation, spinal neural tube

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3 juillet 2015

What Makes LipiFlow® and LipiView® II So Successful in Our Practice

What Makes LipiFlow® and LipiView® II So Successful in Our Practice Meibomian Gland Dysfunction | Treatment | TearScience TearScience® is the only company dedicated to identifying, diagnosing, and treating MGD, the leading cause of dry eye, with an FDA-cleared...

Posté par Eric Belot à 15:54 - Commentaires […] - Permalien [#]

Tags: Tearscience website, Tarsal glands Meibomius glands dysfunction, Dry eye, diagnosis, DED, 2015, Devices, LipiFlow

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23 novembre 2015

NEW PUBLICATIONS UPTO NOV. 21ST 2015

NEW PUBLICATIONS UPTO NOV. 21ST 2015 The Cataract Patient is a Dry Eye Patient By Josh Johnston, OD, FAAO 11/15/2015 A 63-year-old female presented in the clinic for an eye exam for the first time in five years with a best-corrected visual acuity of 20/40...

Posté par Eric Belot à 15:54 - Commentaires […] - Permalien [#]

Tags: publications, Dry eye, DED, 2015, Cataract, News

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24 septembre 2015

NEW PUBLICATIONS UPTO SEPTEMBER 18TH 2015

NEW PUBLICATIONS UPTO SEPTEMBER 18TH 2015 The effects of long-term topical glaucoma medication on conjunctival i Long-term use of topical drugs can induce changes in theconjunctiva and ocular surface. To determine theconjunctival changes resulting from...

Posté par Eric Belot à 22:26 - Commentaires […] - Permalien [#]

Tags: publications, Dry eye, DED, New Therapies, News, artificial tears, cyclosporin, pain

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9 septembre 2015

NEUROPTIS BIOTECH TO SELL ML7 FOR R&D ACTIVITIES

NEUROPTIS IS THE OWNER OF PATENTS ON THE SYNTHESIS OF PURIFIED AND STABLE ML7 ACCORDING TO THE REQUIREMENTS OF EMEA AND FDA WITHOUT ANY DEGRADATION PRODUCT NEUROPTIS HAS ALSO DEVELOPED METHODS OF DOSAGE OF ML7 (HPLC) IN DIFFERENT BIOLOGICAL LIQUIDS NEUROPTIS...

Posté par Eric Belot à 15:24 - Commentaires […] - Permalien [#]

Tags: patents, ML7, formulation, Synthesis, MLCK inhibitor, Price

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8 juin 2015

NEWS UPTO JUNE 7TH 2015

NEWS UPTO JUNE 7TH 2015 1. BMC Ophthalmol. 2015 Jun 6;15(1):58. Effectiveness and relevant factors of 2 % rebamipide ophthalmic suspension treatment in dry eye. Ueda K 1, Matsumiya W 2, Otsuka K 3, Maeda Y 4, Nagai T 5, Nakamura M 6. Author information:...

Posté par Eric Belot à 18:35 - Commentaires […] - Permalien [#]

Tags: publications, Dry eye, treatment, DED, 2015, New Therapies

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3 avril 2015

TEARLAB DEVICE

Link: http://www.tearlab.com Product Information What is TearLab? Manage Your Dry Eye Patients with Confidence The TearLab Osmolarity System is the first objective and quantitative test for diagnosing and managing Dry Eye patients. Fast and accurate results...

Posté par Eric Belot à 13:55 - Commentaires […] - Permalien [#]

Tags: Medical Device, Dry eye, diagnosis, DED, Ocular Technologies, Osmolarity, TEARLAB

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4 mai 2015

NEWS DRY EYE UPTO MAY 4TH 2015

PubMed Ther Clin Risk Manag. 2015 Apr 13;11:595-603. doi: 10.2147/TCRM.S77091. eCollection 2015. http://www.ncbi.nlm.nih.gov 1. Clin Ophthalmol. 2015 Apr 15;9:665-75. doi: 10.2147/OPTH.S78184. eCollection 2015. Efficacy and safety of two new formulations...

Posté par Eric Belot à 17:29 - Commentaires […] - Permalien [#]

Tags: publications, Dry eye, DED, 2015, Safety, Statistics, Clinical Trial

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20 avril 2015

NEW THERAPEUTIC OPTIONS FOR DRY EYE

14. [Full body hydration and dry eye]. [Article in German] Messmer EM. Comment on Author response: is whole body hydration an important consideration in dry eye? [Invest Ophthalmol Vis Sci. 2013] Is whole-body hydration an important consideration in dry...

Posté par Eric Belot à 12:22 - Commentaires […] - Permalien [#]

Tags: publications, Dry eye, treatment, DED, 2014, Full body hydratation, Physiotherapy

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26 mai 2015

BENEFIT FROM THE COMPREHENSIVE OFFERING OF DRUG DISCOVERY PRODUCTS AND SERVICES

Eurofins France Le groupe français de biotechnologies Eurofins Scientific, fondé à Nantes en 1987, figure parmi les premiers prestataires mondiaux sur le marché de la bioanalyse. http://www.eurofins.fr BENEFIT FROM THE COMPREHENSIVE OFFERING OF DRUG DISCOVERY...

Posté par Eric Belot à 21:07 - Commentaires […] - Permalien [#]

Tags: publications, 2015, Research, Cerep, Acquisition, Drug Discovery, Europhins

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1 juin 2015

NEW PUBLICATIONS UPTO MAY 31TH EPUB

NEW PUBLICATIONS UPTPO MAY 31TH IOVS | Effect of Topical 5-Aminoimidazole-4-carboxamide-1-β-d-Ribofuranoside in a Mouse Model of Experimental Dry Eye http://iovs.arvojournals.org Invest Ophthalmol Vis Sci. 2015 May 1;56(5):3149-58. doi: 10.1167/iovs.14-16153....

Posté par Eric Belot à 21:19 - Commentaires […] - Permalien [#]

Tags: publications, Dry eye, treatment, DED, 2015, New Therapies

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5 mai 2015

NOVAGALI/SANTEN

Home | France | SantenPharmaceutical http://www.santen.eu PIPELINE: pipeline To Meet Global Medical Needs with Our Networks Covering Japan, the United States, Europe, and Asia Developing new pharmaceuticals entails a long period of over 10 years, as well...

Posté par Eric Belot à 20:44 - Commentaires […] - Permalien [#]

Tags: Biotech Finances, Dry eye, DED, Research, Drug development, Japan, PublicPrivate

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5 juin 2015

A Stepwise Approach To Acute Dry Eye

A Stepwise Approach To Acute Dry Eye A Stepwise Approach To Acute Dry Eye Dry-eye disease is well-recognized as a complex, chronic disease that needs chronic therapy. Superimposed on the intricate landscape of oxidative processes, immunological priming,...

Posté par Eric Belot à 16:47 - Commentaires […] - Permalien [#]

Tags: publications, Dry eye, diagnosis, DED, 2015, ORA

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6 juillet 2015

NEW PUBLICATIONS UPTO JULY 4TH 2015

NEW PUBLICATIONS UPTO JULY 4TH 2015 ON THE STAGE THIS WEEK: Current and Emerging Therapeutic Strategies for the Treatment of Meibomian Gland Dysfunction (MGD). Temperature profiles of patient-applied eyelid warming therapies. IOVS | The International...

Posté par Eric Belot à 15:48 - Commentaires […] - Permalien [#]

Tags: publications, Tarsal glands Meibomius glands protection, Meibomian, Tarsal glands Meibomius glands dysfunction, Dry eye, DED, New Therapies

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